What might indicate an effective response to treatment in a patient with Major Depressive Disorder?

An effective response to treatment in a patient with Major Depressive Disorder can be indicated by a reduction in social withdrawal. This behavior suggests that the patient is beginning to engage more with social interactions, which is often an important aspect of recovery from depression. When individuals start to feel better, they typically show increased interest in socializing and connecting with others, as they regain energy and motivation.

This shift can signify improvement in mood and functioning, highlighting progress in the treatment regimen. As social withdrawal lessens, patients may express improved communication skills, enhanced ability to form relationships, and a better overall outlook on life, which are all positive signs of recovery.

Other options, such as persistent feelings of hopelessness, increased late-night sleep disturbances, and continued irritability and anger, generally represent ongoing struggles with depression rather than improvement. These symptoms indicate that the patient may still be experiencing significant challenges and may require further intervention or adjustment in treatment strategies.